Major hospitals have issued documents one after another. According to the medication indications formulated by Xu Qiu in the popular science article, they have used naproxen therapy on some patients with clinical symptoms and unexplained fever, and have achieved quite significant effects.

Needless to say, in Baiyun Province, at the request of the National Health Commission and the health department, naproxen was included in the provincial medical insurance, the price was further reduced, and a large number of drugs were booked in advance.

Outside the province, many hospitals were surprised to find that the effect of this drug was far from as simple as fighting cancer-related fever.

Clinically, it has a more obvious advantage.

That is to say, it is used as a verification method to determine whether the patient has cancerous fever, so that some tumors that cannot even be detected by imaging can be detected early...

For example, Tao Changhan.

His tumor indicators are very low, and he is generally not considered to have cancer clinically. Even if he does, it is a very early-stage cancer with no detection and treatment significance.

Doing CT, MRI, etc. is time-consuming, labor-intensive, and expensive.

However, if you have unexplained fever, taking naproxen can effectively treat cancer-related fever and diagnose cancer early. This is more reliable and more convenient than other examinations.

Because of this, many cancer hospitals and fever clinics have seen a sudden surge in demand for naproxen.

The manufacturer is not aware of this.

This has also resulted in all naproxen in pharmacies being sold out. Even Baiyun Province, which had prepared for a rainy day and signed a purchase contract long ago, is facing a shortage of supply.

When the effects of naproxen received more positive clinical feedback, the Baiyun Provincial Health Commission, the Gynecological Cancer Prevention and Research Society, the Oncology Society, etc. jointly issued a document and formulated a new clinical guideline as quickly as possible!

Criteria for treatment with naproxen:

1. The body temperature is higher than 37.8 degrees Celsius once a day

2. Fever lasting for more than two weeks (or repeated fever in severe patients)

3. Physical examination, body fluid culture and imaging did not suggest infection.

4.Exclude drug allergies, blood transfusion reactions, reactions to radiotherapy and chemotherapy

5. A week of adequate antibiotic treatment is ineffective; or other cooling measures are ineffective.

…

This new medication indication quickly entered the oncology guidelines of Baiyun Province, and then affected several surrounding provinces.

Although other provinces have not followed up, the latest guidelines from Baiyun Province have been used within hospitals.

For a time, domestic sales of naproxen surged thousands of times.

Titles such as "the medicine of conscience" and "the good medicine of the common people" have been attached to naproxen. Some people have even called it a miracle medicine.

The only regret is that although the domestic oncology department was inspired by a lecture by Xu Qiu and a popular science that led to a new medication direction, naproxen did not create much of a stir abroad.

In other words, there is no news at all from foreign hospitals.

Once Naproxen, which costs a few dollars, becomes widely available, it will shake the interests of many pharmaceutical giants and directly impact many drugs that use this as their selling point.

It can even affect the imaging department and laboratory department.

After all, many patients with unexplained fevers cannot be solved in the end, and they just need to continue to undergo laboratory tests and imaging analyses. After Naproxen’s reputation started in Linhai No. 1 Hospital, this cheap drug will replace various expensive drugs. Check it out and become the first choice.

…

In the past few days, Tao Changhan, as the first patient in the history of Linhai No. 1 Hospital to use naproxen to cool down, and directly promoted the development of new drug indications and clinical guidelines, received special care.

The doctors at Linhai No. 1 Hospital were almost grinning.

Many doctors are worried about having no cases and no direction for their papers.

Now it suddenly becomes clear.

In just a few weeks, a large number of related papers have been studied.

"The application of naproxen in the differential diagnosis of cancerous fever";

"Application of Naproxen Test in Differential Diagnosis of Cancerous Fever and Infectious Fever in Lung Cancer";

"Observation on the therapeutic effect of naproxen in the treatment of advanced colorectal cancer tumor heat"...

This also made Tao Changhan's ward quite lively.

Tao Changhan's daughter almost smiled crookedly. She was always open to doctors who came to ask about medical history and study data.

"If this were the case before, you female doctors might have been molested by my father several times. Unfortunately, now that he has mutism, you won't be able to endure it!" Tao Nu joked.

On the hospital bed, Tao Changhan looked hopeless.

He is just taciturn, not deaf!

Could you please stop saying bad things about me in front of me?

"Doctor Xu!"

At this moment, the door to the ward was pushed open, and the female doctors in the ward immediately dropped Tao Changhan and greeted him with joyful faces.

"Um."

Xu Qiu didn't even raise his head. When he walked into the ward, his eyes scanned Tao Changhan's examination report.

Various forms showed that there were no major problems and the patient was in compliance with the indications for discharge.

However, Xu Qiu still felt uneasy, so she planned to come over in person for a final full-body examination before signing the discharge notice.

"Is that Tao Changhan?"

Although Xu Qiu had already memorized the patient's appearance, he did not skip the necessary procedures.

"Check again before discharge. If there is no problem, follow up."

Tao Changhan opened his eyes a little and made no gnawing sound, but his body still made a cooperative gesture.

Xu Qiu focused on examinations related to the head, face and nervous system.

There is no tenderness or mass in the head.

The cornea has no turbidity or scars.

pupil……

Xu Qiu was stunned for a moment, and with just one glance, he realized something was wrong with the patient.

"look up."

"look down……"

After a few simple examinations, Xu Qiu wrote down two diagnoses on the examination form.

Unable to look upward;

dilated pupils;

Eye movement disorders;

These are the most characteristic manifestations of nuclear damage.

Limitation of upward vision on the contralateral side is caused by destruction of the superior rectus nucleus on the side of the lesion, or numbness of the oculomotor nerve.

The patient himself had no eye trauma and no underlying diseases related to the nervous system, so the cause of all this was obviously an intracranial tumor.

This is a very bad sign.

"Where's the urine volume?" Xu Qiu asked.

The little nurse gave the answer: 2800 ml.

As if she guessed what Xu Qiu was worried about, she added: "Dr. Xu, Sister Su Su reminded us that we should pay special attention to diabetes insipidus, which is a manifestation of the hypothalamus being compressed and invaded by tumors.

Therefore, the nursing team is very concerned about urine output.

After verification, the patient's 24-hour urine output was slightly higher than normal, but far from the standard for diabetes insipidus!"

A normal person's daily urine output is about 1500~2000 ml.

For patients with diabetes insipidus, the daily urine output is more than 6000 to 8000 ml.

Tao Changhan's urine output was only 2,800. Although it was more than the average person, it was still too little to diagnose diabetes insipidus.

However, Needle shook his head and judged: "No, the tumor may have affected the hypothalamus."

The little nurse's expression changed, and the other doctors in the ward were also stunned.
Chapter completed!