Chapter 897 Human Pharmacological Experiments
Yang Yuanzhao, who received the news, had already gone to bed. After receiving the news, he got up as soon as possible. He knew very well that although sulfonamide was the first broad-spectrum antibacterial drug, it had too many side effects, the scope of treatment was relatively small, and the effect was not good. This was also when penicillin and derivatives became popular in later generations, sulfonamide almost disappeared. In addition to a few specialized diseases and traces of sulfonamide, sulfonamide was rarely used among other prescription drugs. n∈n∈, there was no choice before. In my meager historical knowledge, I found a suitable antibiotic. If there was another choice, penicillin would definitely replace sulfonamide.
As the starter of this issue, he has almost carried out penicillin research on almost his own in four years, and even invested more than 20 million US dollars every year in this project. The total amount of US$100 million in four years has been received. However, when the development of penicillin broke through the original dilemma and initially purified and crystallized to the level of human use, he still couldn't suppress his excitement and came directly to the No. 1 Biological Research Institute in Northwest.
As the most important biological laboratory in the northwest, which studies antibiotics and even sulfonamide preparations, the security level of the first laboratory is quite high. There are at least triple protection around the entire institute. Even inside the institute, there are regular internal security forces protected by a battalion all year round. It is also at the core of the northwest, with the most strict protection in Baotou. It can be said that the protection is extremely strict.
Yang Yuanzhao's arrival alarmed many people. The northwest is no longer the same as Baotou, which has not yet radiated out of Inner Mongolia. The northwest is now the center of the entire China. It is recognized by the great powers. The existence of Yang Yuanzhao. As for the northwest, it is a giant and the Dinghai Dinghai Knife.
Any of his movements is followed, and there are even many big names. Because of Yang Yuanzhao's sudden visit, he developed some interest in the First Biological Research Institute. However, after carefully understanding everything about the First Biological Research Institute. Especially after four years of cumulative investment of hundreds of millions of US dollars, another important project of the First Biological Research Institute is in-depth research on drugs such as sulfonamide. After knowing this, all the big names who are qualified to pay attention to Yang Yuanzhao have almost all retreated. In the past three years and even more, these two major fields can be called the pillars of the entire Northwest. It is precisely because of the emergence of these two commodities that have split the pace of Northwest's sales in the world like a leader.
Sulfonamide is a life-saving medicine for many incurable diseases. Stockings are an indescribable temptation for Western women. When others cannot produce them, these two commodities have become an inevitable choice that cannot be replaced. Even if their producer is a country that has never been heard of, it must be sought after.
Because of this, the Northwest has easily tore open the markets of other countries through baled sales and other means, using these two products as the leader. Entering or not entering is the initial level. After successfully passing this initial level, everything is natural, China's huge population resources. The assembly line based on later concepts and advanced production machines brought by Yang Yuanzhao, all of which make the Northwest's products good quality and low price and extremely competitive. In this case, the Northwest's products became popular all over the world.
The same institute as the research of sulfonamide has invested 100 million US dollars accumulatively. These two points are like two huge weights, hanging high. Everyone knows that Yang Yuanzhao attaches great importance to him is definitely unprecedented. As long as this drug has half the power of sulfonamide before, whether it is investment or Yang Yuanzhao's attention, these are not something that any of them can peek at.
The news of Yang Yuanzhao's arrival soon spread at the First Institute of Biology. Song Wan, the head of the First Institute of Biology, and Zheng Yu, the head of the research of penicillin, came to the door to greet him. Even if it was a daily life, Yang Yuanzhao was very concerned about penicillin. Not only did he order the secretary to observe the progress of penicillin at any time, he himself, in the past four years, has also visited the institute six times. Both Song Wan and Zheng Yu knew him.
In the past six years, the Northwest has developed too fast. In just six years, it has developed from a poor country with no industrial foundation to a country with multiple categories and different types of industries. Researchers who have emerged with the development of the Northwest have gradually become domestic researchers from the beginning. A small number of Chinese people with sufficient foundations have gradually mastered scientific research methods through high-intensity research. Combining the two, the best group of young scientists in China have been born.
China does not lack a position, but the people who command research. If the Northwest has enough researchers, Yang Yuanzhao can develop most of the projects in the future in the Northwest. Unfortunately, so far, about half of the research institutes are under the leadership of foreign countries. Some projects with far-reaching significance to the country and the system, as well as some forward-looking projects, cannot be continued at all.
I briefly greeted two people and asked about the process of penicillin purification. At any time, money and people are ready-made. These two things always have a huge effect on projects with certain goals. The initial research was only very slow to purify and isolate the strains. Next, after a certain understanding of penicillin, the speed accelerated. The hard work finally came to fruition. After a series of failures, the northwest was divided into hundreds of research groups, starting from the import of melons around the world, and made a breakthrough. In a kind of melon, a large-scale extraction of penicillin was discovered. The yield of penicillin began to increase greatly, from the original laboratory production to small batch production. This time, it was even more advanced from melon to corn configuration solution, and went further in specific corn configuration solutions. Not only did the concentration meet the standards, but the yield also increased significantly.
Now, the unit of penicillin has improved from ten to thousands, and gradually moved closer to ten thousand. The pharmacology and animal experiments on penicillin have been carried out almost the same. It is fundamentally confirmed that penicillin has a broad-spectrum antibacterial ability to a large number of bacteria and has no effect on the human body. Because the effect of penicillin refers to the fact that penicillin contains penicillin, which can destroy the cell wall of bacteria and play a bactericidal role in the reproduction period of bacterial cells. However, there is no cell wall in humans and animals, so it has no effect.
Looking at the excited Song Wan and Zheng Yu, Yang Yuanzhao was as happy as them. He was another butterfly wing, at least 30 years ahead of schedule. It was born enough to have an effect on the human body and kill most antibiotics in this era. Of course, Yang Yuanzhao has also heard of the consequences of antibiotic abuse. The war between bacteria and humans is a war of two different systems. Antibiotics are almost impossible to kill all bacteria, and the rest will be resistant, but the emergence of penicillin is a good thing.
“How much is the yield and purity?”
"If all the laboratories of the First Biological Laboratory are produced according to the existing methods, they can produce about 120,000 units of penicillin every day!"
Yang Yuanzhao nodded. He knew that the First Biological Laboratory is huge in scale and has more than 200 different laboratories. Penicillin is in a certain sense. As long as the preliminary research is completed, it is not a special thing to produce it. Otherwise, there will not be so many million units, or even tens of millions of units in the future, and the price will be so cheap. He nodded and said, "Calculate the conversion from laboratory to factory production as soon as possible and start production as soon as possible!"
"But!" Zheng Yu looked at Yang Yuanzhao hesitantly, not knowing whether to say it or not. Penicillin has completed all the preparations. The effect of penicillin in thousands of units of penicillin on the human body is definitely strong enough. However, they have only conducted animal experiments before, but they have not conducted physical experiments. With Baotou's emphasis on human rights issues, they rashly entered the medical system. It was a disaster.
After hesitating, Zheng Yu still mentioned his own opinion. Yang Yuanzhao listened and was stunned for a moment. He knew very well what the side effects of penicillin were and also made some suggestions. For penicillin, there would be certain adverse reactions, and there would be nothing else. However, the researchers below did not know. As the Northwest increasingly noticed the rights of ordinary people, it was impossible to target the people on a large scale. At this time, prisoners of war became sick and asked the Northwest government for medicine.
Starting from the production of sulfonamide in the northwest, the research on this sulfonamide has not stopped. From the beginning, most of the sulfonamides were synthesized by Yang Yuanzhao. Later, the northwest produced and purified by itself. With the role of various advanced machines, the cost of sulfonamide is quite low. In this case, it is not difficult to provide to prisoners of war. It was not as high as Yang Yuanzhao, but after the Institute of Biology learned about it, I felt that this was an opportunity. The original purpose of the prisoners of war was not to solve the labor problem in a more dangerous field in the northwest. Now they are sick and need medicines. In the spirit of humanitarianism, let's give them the latest special medicines.
Chapter completed!