Chapter 171 A major breakthrough in AIDS
Level 4 Biosafety Laboratory of the Institute of Life Sciences, Spark Research Center.
Wang Xiaoxiao led members of the AIDS project team to wear closed protective clothing to observe the development of HIV in the body of African green long-tailed monkeys in the laboratory.
The experiment has entered the critical moment. If this experiment is successful, it will basically prove Wang Xiaoxiao's conjecture, and humans can also find ways to control HIV.
There are more than 10 African green long-tailed monkeys in the cage in the laboratory.
This monkey's lymph T cells can serve as the host of HIV, but the HIV virus cannot reproduce in large areas in the body of African green long-tailed monkeys, threatening the health of African green long-tailed monkeys.
There are many such viruses in nature. They only pose a fatal threat to one species and do not affect other species at all.
For example, tobacco mosaic virus, only tobacco can be infected with this virus. African swine fever virus, only pigs can be infected with this virus. Even if people are close to contact with this virus, there is no danger.
"Test the concentration and activity of HIV in the body of African green long-tailed monkeys." Wang Xiaoxiao ordered.
The scientific research assistant immediately operated the equipment and began to extract blood and lymph from African green long-tailed monkeys to conduct detailed testing of the HIV concentration in the body of African green long-tailed monkeys.
The Institute of Life Sciences has a method for rapid detection of HIV, and the detailed concentration and activity of HIV are immediately given in the instrument.
The researcher will report soon: "Director, the HIV concentration test of all African green long-tail monkeys has been completed, and the HIV concentration and activity in all African green long-tail monkeys is basically the same."
"The control group observed that the African green long-tailed monkey No. 1 and 2 were injected with human herpes virus-6 virus.
No. 3 and 4 African green long-tailed monkey were injected with human herpes virus-6 virus pheromone.
No. 5 and 6 African green long-tailed monkey were injected with human herpes virus-6 virus knocked out of pheromone and interferon genes, as well as human herpes virus-6 virus interferon.
Inject inducible corneum to No. 7 and No. 8 African green long-tail monkey.” Wang Xiaoxiao immediately ordered.
Wang Xiaoxiao stared at the African green long-tailed monkey. If the project was successful or the experimental direction was changed again, it depends on the results of this experiment.
With the support of the powerful capital of Spark Technology, he can finally explore the problems he has always been puzzled about.
After several months of intensive research and development, Wang Xiaoxiao also discovered the relationship between HIV and human herpes virus-6 virus.
If HIV is compared to the army, human herpes virus-6 virus is a scout.
Only when the scouts poke out the enemy's vision and disguise their own army, can the army exert their strong combat power.
The human herpes virus-6 virus releases a pheromone that can increase the reproduction of HIV by dozens of times.
The human herpes virus-6 virus also releases an interferon. When HIV and human herpes virus-6 virus coexist, the human immune system preferentially attacks the human herpes virus-6 virus.
It protects the rapid replication of HIV through self-sacrifice.
Finally, HIV breaks the balance and quickly conquers the immune system.
This is the long-term tug-of-war between the immune system of HIV carriers and has not shown any symptoms of AIDS.
But after they were infected with human herpes virus-6 virus, the HIV virus broke out completely and quickly formed the cause of AIDS.
Wang Xiaoxiao is based on the relationship between HIV and human herpesvirus-6 virus.
He also studied the entire process of the immune system dealing with HIV, the biotin link between HIV and human herpesvirus-6 virus.
Inducer has been developed, which can disguise the connection between HIV and human herpesvirus-6 virus and mark HIV.
Once the inducer is found, the antibodies produced by lymphatic T cells and lymphatic B cells will attack wildly. Through this method, the disease of AIDS can be controlled.
When the researchers heard Director Wang Xiaoxiao's instructions, they immediately took action, each responsible for a group of African green long-tailed monkeys, observing the HIV situation in the African green long-tailed monkeys every half an hour.
A day later, the HIV situation in the African green long-tailed monkeys has changed.
Taking the control group as the reference point, the HIV virus in the body of African green long-tailed monkeys No. 1 and No. 2 increased by 25 times.
No. 3 and 4, the HIV virus in the African green long-tail monkey increased by 20,000 times.
No. 5 and 6, the HIV virus in the African green long-tail monkey increased by 25%.
No. 7 and 8, the HIV virus in the African green long-tail monkeys decreased by 50%.
Three days later, the HIV situation in African green long-tailed monkeys has undergone significant changes.
Taking the control group as the reference point, the HIV virus in the body of African green long-tailed monkeys No. 1 and No. 2 increased by 32 times.
No. 3 and 4, the HIV virus in the body of African green long-tail monkeys increased by 230,000 times.
No. 5 and 6, the HIV virus in the African green long-tail monkey increased by 5 times.
No. 7 and 8, the HIV virus in the African green long-tail monkeys decreased by 80%.
A week later, the HIV situation in the African green long-tailed monkeys became more clear.
Taking the control group as the reference point, the HIV virus in the body of African green long-tailed monkeys No. 1 and No. 2 increased by 18 times.
The immune system of African green long-tailed monkeys has adapted to the new situation and has begun to react. The lymphatic T cells have crazily differentiated, proliferated, and transformed, and have begun to suppress the replication of HIV.
The African green long-tail monkey, which did not have AIDS, has died of AIDS. The African green long-tail monkey, who had no AIDS, was conquered by countless HIV viruses. The huge number of immune cells has decayed, resulting in the death of sepsis in the African green long-tail monkey.
No. 5 and 6, the HIV virus in the African green long-tail monkey increased by 13 times.
The immune function of African green long-tailed monkeys has also been improved, but most of their strength is to attack the human herpes virus-6 virus.
No. 7 and 8, the HIV virus in the African green long-tail monkeys decreased by 98%, and it is already difficult to detect HIV through conventional methods in the blood and lymph.
However, blood cell lysis was performed, and the ribonucleic acid (RNA) fragment of HIV was detected in the tissue fluid, proving that HIV still exists in the body of African green long-tailed monkeys.
When Wang Xiaoxiao saw the results of the experiment, he shed tears of excitement and choked and said, "The experiment has been successful, and humans have finally found a way to deal with HIV.
I will continue to work hard to make HIV the second most widely spread infectious disease after smallpox virus to be completely eliminated by humans.”
After disinfection, Wang Xiaoxiao walked out of the biological reagent safety laboratory and he immediately called Zhou Yu.
After the phone was connected, Wang Xiaoxiao said excitedly: "Mr. Zhou, our experiment has been successful and we have found a way to control HIV."
Zhou Yu was woken up from his sleep. When he heard Wang Xiaoxiao's report, he immediately said excitedly: "You sort out the experimental data and I'll arrive soon."
Zhou Yu quickly put on his clothes and saw that it is June 28th, at 5:32 am, which is a time that will be engraved by history.
He immediately drove the Xuanwu electric car to the Life Sciences Institute, preparing to learn about the specific situation of the AIDS project from Wang Xiaoxiao.
If the Institute of Life Sciences can really solve AIDS, the reputation and profits it will gain are very considerable for Spark Technology.
Zhou Yu saw Wang Xiaoxiao who had gained weight and asked excitedly: "Director Wang, have you analyzed the relationship between HIV and human herpes virus-6 virus? Can AIDS be completely cured now?"
Chapter completed!