[The rigorous scientific research materials on brain organoids in this chapter are from the "MIT Science and Technology Review" and the magazine "Scientist". They are not original and have been specially commented.]

As soon as he walked into Rudolph's laboratory, Zhou Cunguang's eyes widened.

He entered the organizational training for more than half a year. To be honest, he traveled all over the country and went to several countries to learn languages. Teachers from four languages ​​are always around him, indoctrinating 24 hours a day, and they are also people who have seen the world.

But Rudolph's laboratory is different.

Before Zhou Cunguang came, he knew that this was the most mysterious laboratory in the world. This is not a question of whether he had seen the world. It can be said that even presidents of various countries wanted to come here to see it, but they couldn't.

Zhou Cunguang, who came here, was excited. He had countless fantasies about this laboratory, various high-tech, countless forms of black science and technology, and even painted the appearance of a robot that might exist on paper.

But the scene in front of him exceeded his imagination.

I closed my eyes tightly, reached out my hand and pinched my nose, feeling the vision in front of me a little dizzy. After this, I opened my eyes again and Zhou Cunguang stood there like a wooden carving.

"Don't be afraid, what I need to do in experiments can be more advanced by relying on them to make human brain organoid technology." Rudolph said this, his jaw slightly raised and looked at the wall. Unlike Zhou Cunguang's eyes, Rudolph's eyes were shining brightly, like stars in the sky.

It was this kind of eyes, this kind of eyes full of unparalleled love for scientific research, that made Zhou Cunguang recognize Rudolph instantly.

only……

Zhou Cunguang took a breath and did not dare to look at the wall.

"If you are not a child, it is impossible to come in. This is a top-secret place. Don't move around. I'll look for the medicine box. Go there to see if there is any food. I remember some." As soon as Rudolph entered the laboratory, he seemed to have forgotten about what he had to do with Zhou Cunguang. After he said a few words, he actually sat in front of the monitor and looked up.

Zhou Cunguang looked around and found that the laboratory was really big and could be described as magnificent. Unlike the experiments of scientists he saw in China, the area was ten times as big as that of Rudolph.

In addition to him alone, there are several robots parked around, which is also the difference.

Rudolph was right. If it weren't for Zhou Cunguang being a "child", he wouldn't have entered such a top laboratory. You should know that Professor Zhou's laboratory had not even entered. There could be seen several glass bottles in the distance, with foggy inside, and there was something on it.

His eyes looked at the wall and immediately dodged away.

It's so terrible, really so terrible.

The heads all over the wall...

I saw that the huge bookcases that reached the ceiling were filled with glass bottles, with liquid soaking inside. The size of the glass bottle was just right for a person. Some had faces, some had only half of the face, while some had skin peeled off, some had half a piece of cut, and more were a pile of brain tissue soaked in it. There were some introductions on the lower part of each glass bottle, which was too far away to see clearly.

Zhou Cunguang has never seen the title of the human body, and has imagined the appearance of brain tissue being taken out, but he has never seen hundreds of such human brains.

Hundreds! Two walls that were nearly three meters high, and each glass bottle was full of these things. It looked like hundreds of people staring at them. It would be better if they were full of people. The problem was that one piece was missing here and there was a little.

As can be seen from the hair, there are old people, men, women and children here.

What is the black and gray one by one that is soaked in the small bottle? When I looked closely, my heart tightened and there were actually a bunch of eyeballs.

It's so traumatic, it's really so traumatic.

Zhou Cunguang couldn't help but put his legs together tightly, and he had the illusion of wanting to go to the bathroom. This illusion was only like this when he was extremely nervous. He quickly looked away again, feeling his whole body numb, and his throat was itchy and his stomach was churning.

Wow……

He suddenly vomited, fortunately there was a trash can nearby, but it was also spread out to the ground. A robot in the distance immediately slid over to clean it. However, Rudolph, who was sitting in front of the microscope not far away, seemed to be unable to hear all the sounds around him, and was still sitting there detecting something.

Zhou Cunguang slowed down and stabilized his emotions. After looking around quickly, his eyes fell on the labels on the glass bottle of human brain tissue filled with bookshelf. He walked over quickly and wanted to open the bookcase to look, but found that it just looked like a bookcase. In fact, it was a huge thermostat, just made into the style of a bookcase.

It can't be opened at all.

There is something similar to fingerprint* on the left, with one layer of dark boxes. It seems that only Rudolph wants to open this thermostat.

I lay on the glass and looked in, and saw some content written on the glass bottle that Zhou Cunguang couldn't understand, such as totipotent stem cell, TSC; and pluripotent stem cell, etc.

"Get close illegally! Get close illegally!" Perhaps Zhou Cunguang put it on the entire glass so fiercely. Suddenly, the thermostat warned. The sudden sound and the heads of the cabinet made him tremble.

"Don't move!" A very stern voice came.

Zhou Cunguang turned his head and saw Rudolph wearing glasses, his face full of anger and seriousness, as if a beast was about to protect his cub.

"I……"

"Come here, I told you not to move around!" Rudolph grabbed Zhou Cunguang and dragged him to the side. It was completely different from the kindness he had treated him before. It was very fierce. He stretched out his hand and pushed his glasses: "These are my treasures. You don't have to be afraid or curious. You just need to use things you need to study."

"Did you... cultivate... cultivate... or..." Zhou Cunguang's voice trembled slightly.

If these were cultivated by him, it would be a little better, but it wouldn't seem to be cultivated by him when he looked left and right.

Although the field of human brain organoids is profound and ordinary people don’t understand it, they also know that this is to solve some problems that arise within the brain and what are the consequences. For example, why is Zhou Cunguang a dwarf? The pituitary gland of the brain has problems. What specific problems arise? What drugs do you need to use for treatment?

The current scientific community has not solved this, which is why Zhou Cunguang understands that his disease has no cure.

How to solve this problem?

The traditional method is to detect the brain of a dwarf and dissect the brain to see where the problem appears. But the brain is too complicated. Even if you see where there is a problem, what causes these problems? Is it a problem at which part of the brain development? Is it a problem with the pituitary gland alone, or is it a problem caused by the slow influence of other brain structures?

These problems are difficult to achieve by dissecting a dead brain.

Only by pursuing the source of these problems and discovering what causes and which cells cause dwarfism can we develop drugs for research and development. Research and development of drugs is what another group of scientists needs to do. The scientists who develop drugs need to find out the cause first by brain experts like Rudolph.

These are linked together.

In the villa area, the world's most mysterious and huge laboratory, next to the brain organoid laboratory is the laboratory of drug scientists.

Going back to the previous question, these problems are difficult to achieve by dissecting a dead brain, so what can I do? This returns to the direction of Rudolph's research: brain organoid research.

Artificially cultivate brain tissues through cell cultivation, and artificially start to be conceived from the smallest time of the brain, so that you can see which link is wrong. For example, cells from dwarfism patients are obtained and organoids with consistent characteristics with the patient's brain are cultivated. By replacing the defective proteins in the backbone faces of the county of this disease, some organoids that are as related are cultivated.

Of course, it is easier said than done.

Can……

Rudolph looked at the wall of human heads and felt his heart tremble. He remembered that the organization had given him information before coming to the organization, saying that Lancaster had published an article saying that the human brain did not need craniotomy to remove the human brain for cultivation, but only some cells were needed from the skin, and then after cultivation, it could be cultivated into a brain organoid with a shape and function similar to his brain.

This made Zhou Cunguang feel that the research on human brain organoids is not so bloody, just take some human skin.

When Zhou Cunguang first saw this, he felt incredible and full of pride. Is the technology now so developed? Just a little skin can cultivate a brain similar to you? Although it is not a completely useful brain, since cells can be removed from the skin can be used to cultivate brain organoids, how can there be so many brains dissected here?

"Of course these were not cultivated by me. Didn't you see that there is still skin and hair here? The research I did is to cultivate human brain organoids and cellular tissues." Rudolph obviously felt very ignorant and ridiculous about Zhou Cunguang's problem.

“That’s all…”

"Human, I'm always fresh when I come, it's great!"

A cool air came, just like passing by a large freezer with yogurt in a supermarket. Zhou Cunguang instinctively took a step further away from the bookcase, trying to avoid this cool air, but in vain.

The cold air came from his heart, not a thermostat like a bookcase.

"I heard that you only need to take a little skin from a human to get the tissue that cultivates the organoids of the human brain. How do you need it... need... need..." Zhou Cunguang didn't dare to look at the soaked heads all over the wall, and his voice was a little lighter. It was obvious that he could hear the fear in his heart. He swallowed his saliva with difficulty. Perhaps it was a psychological effect. He always felt that the saliva he swallowed seemed sticky, like the taste of an uncooked pig brain that he had eaten.

"Of course, human heads are needed." Rudolph once again laughed bitterly by Zhou Cunguang's ignorance: "From tissues that can use human skin to make organoids, a large number of human heads have been studied in the middle, which is indispensable in the laboratory; Besides, the study of human brain organoids is a long way to go, and human brain anatomy research is a routine state."

Behind scientific research, there must be animal experiments. People use mice or rabbits for research, and it is no longer a secret that a large number of animals are used for scientific research. Apart from animals, the human body is also a treasure snatched by major hospitals and research sites.

In a good medical university, how many bodies are stored in the school is an important indicator for medical students to conduct research. Not to mention the research institute, scientists analyze the human body by dissecting and analyzing the human body in order to benefit humans in the future.

"These... but baby! How can you grab so many fresh heads outside for research?" Rudolph shook his head disdainfully: "It would be nice to have five fresh corpses in a laboratory every quarter. Now there are not many people who voluntarily offer their bodies for research."

As I was talking, I could only hear the sound of the door opening.

A door opened, a section of rails floated out on the ground, and several thermostats slid in quickly.

"Tsk tsk, look, there are endless fresh corpses here! How great! How great!" Rudolph ran towards the thermostat, with a happy smile appearing on his face, and shouting: "Great, great, there are five children today, five! That's great!"

He lay on the thermostat and turned around.

The smile is full of happiness.
Chapter completed!