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Chapter 727: Human Medicine Enters the Era of Neuromodulation

Essette's whole body was chilled.

But he still forced a smile and waved upstairs.

At the height of the seventh floor... He just made a phone call. There was absolutely no way that Xu Qiu could hear what he just said and couldn't get into trouble!

Xu Qiu, who was upstairs, also saw Essette's actions, responded with a smile, and then turned around and returned to the laboratory.

Essette breathed a sigh of relief.

When he came to his senses, his back was already covered with a layer of cold sweat.



"Selection of nuclear cluster location..."

In the laboratory, Xu Qiu didn't take Essette to heart at all and immediately started the next step of screening.

He first anesthetized SPF male rats with 9% chloral hydrate.

Then, fix it on the brain stereotaxic instrument.

laugh--

The next moment, the scalpel cut open the rat's skull.

Remove the bone flaps in sequence.

Layers of grease seeped out.

Xu Qiu wiped it clean with 3% hydrogen peroxide, and finally selected different nuclei on different rats.

This step is still very difficult. Not only must the points be selected, but a series of parameters must also be adjusted.

For example, for the medial forebrain bundle, the frontline position should be controlled at -1.8, the side opening distance should be 2.0, and the depth should be controlled at around 8.0...

The barrel area and other sites of the first somatosensory cortex on the left and right sides are also different.

Sizzling——

The sound of the high-speed cranial drill sounded, and soon, holes with a diameter of about 0.9mm appeared on the surface of the rat's skull.

After doing all this, Xu Qiu controlled the brain stereotaxic device and slowly stimulated the target nuclei...



At the same time, in order to improve the data progress, Xu Qiu also made new parameter settings for the brain pacemaker.

The stimulation pulse period is 10ms.

The number of bidirectional stimulation pulses is 15.

The period of the stimulation train is controlled at 1000ms, and the current is 100ua.

"This nuclear group is wrong..."

“Effective, but not sensitive enough!”

“Duration too short!”

After eliminating them one by one, night fell in the blink of an eye. When the sky was slightly bright, Xu Qiu raised her head in surprise.

"Success!"

The subthalamic nucleus is the most suitable nucleus for the brain pacemaker!

After the deep brain stimulation pulse device is implanted here, it can release high-frequency electrical stimulation and regulate abnormal neural circuits. It is especially effective for patients with advanced levodopa-responsive Parkinson's disease who cannot effectively control certain symptoms with drugs!

It also has certain auxiliary effects on unexplained epilepsy, tremors, etc.!

Xu Qiu breathed a sigh of relief.

The next step is to wait for the other components to be developed.

However, since other engineers were unwilling to work overtime, Xu Qiu had no choice but to take on greater responsibilities.

Physical potions and energy potions are also being consumed at an alarming rate.

In the early morning of the third day, before other researchers came to work, Xu Qiu had already completed the final finishing work!

"The current brain pacemaker can record EEG signals and ECG signals in real time, and sense the patient's posture information; in addition, it can also perform wireless Bluetooth data transmission and charging, enabling downloading and contactless EEG signals.

Postoperative program control!”

and……

In order to avoid the sequelae that "implanted metal objects cannot be used for MRI examination", Xu Qiu also specially performed anti-magnetic treatment on the brain pacemaker. After the operation, the patient can still safely undergo high-field MRI examination!

"I have completed it and will send the success to Daxia immediately." Xu Qiu immediately sent a message to Daxia.

A few hours later, Shi Lian took a box of confidential documents and, under the arrangement of the embassy, ​​boarded a special plane back home.

When we landed, it was around 11pm in Berry Country, which is also 11am in the morning of Great Summer Time.

The plane stopped near the headquarters of the Ministry of Health. As soon as Shi Lian got off, he was picked up by several soldiers and drove all the way to the headquarters, then passed through the heavily guarded courtyard before finally arriving in front of the conference room.

Seven or eight ministers were already standing ready, all looking at Shi Lian who was carrying the box.

The latter was extremely nervous. He swallowed several times and said in a trembling voice: "Ministers... ministers, Dr. Xu's documents are here..."

"Open it quickly!" The Minister of Health couldn't wait any longer.

Shi Lian put the box on the table. The Minister of Health and the Director of the National Health Commission came forward respectively and entered the two passwords before the secret box unlocked with a click.

"This is what the teacher specified."

Shi Lian selected two hundred and thirty-seven pieces of complicated information from thousands of pieces of information and carefully sorted them out.

Seeing this posture, the Minister of Health sighed with emotion: "No wonder his Linhai small blood vessels and the seven-star film have not been leaked so far."

Academician Boring said with a smile: "He is the only one with this ability to keep secrets secret."

Triple encryption…

Unless someone knows both passwords at the same time and knows which of the more than 3,000 pieces of information are the real results, it will be almost impossible to decipher them.

After all, most of the content of these more than 3,000 pages of information seems to be consistent, with only some parameters and data being slightly modified...

Shi Lian, on the other hand, remembered the correct order of the information.



"Let me see."

Academician Boring couldn't wait. He hurriedly got through the hundreds of pages of information.

"Dual-channel implantable deep brain electrical stimulation pulse device (hereinafter referred to as the pulse device)"

"This pulse device can effectively treat late-stage primary Parkinson's patients whose movement disorder symptoms cannot be effectively controlled by drugs, as well as unexplained epilepsy, tremors and other neurological diseases..."

"The pulse device has a stimulation chip independently developed by Daxia, which can realize different frequency program control of the left and right brains. The polarity, voltage/current, pulse width and frequency of each channel stimulation contact can be independently programmed and have constant

There are two stimulation modes to choose from: voltage and constant current. It also has the storage and selection of up to 13 groups of stimulation programs, providing refined control options for patients’ periodic symptom fluctuations..."

"..."

Academician Boring only read hundreds of pages of documents for a few minutes, and his blood was already aroused.

His eyes were shining... This achievement may mark the official entry of human medicine into the era of neuromodulation!

It will also mean that patients with Parkinson’s disease who cannot be treated by drugs will no longer have the only option of “waiting to die”!

If a brain pacemaker is really developed, Daxia will be at the forefront of the world in the field of neuromodulation technology, and will use this to expand from deep brain stimulation to vagus nerve stimulation pacemakers, spinal cord stimulation pacemakers, sacral nerve stimulation, etc.

Etc., urinary incontinence, pain, diabetes, and motor dysfunction may all be among the indications!

"Let me see!"

The Minister of Health and the Director of the National Health Commission could not wait any longer. Regardless of their status, they crowded next to Academician Boring and started reading the document.

Other ministers took no action.

They wanted to see it, but they couldn't understand it at all.

Matters in the professional field can be left to Academician Boring, the Minister of Health and the Director of the National Health Commission. They also know very well that in the face of such a huge matter, it is impossible for the three of them not to be confused about priorities.
Chapter completed!
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