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Chapter 670 Five billion, five months!

"Failed...failed?!" Han Chang's pupils shrank, and his voice stuttered.

A senior researcher hurriedly said: "Doctor Xu, our experimental results have come out. Blocking cdk20, hepatocellular carcinoma has really died!"

The others wanted to defend themselves.

Xu Qiu has helped them complete the first two steps in the selection of targets. He only needs to verify whether the 121 targets are clearly responsible for hepatocellular carcinoma, and whether it can be affected by the target to curb or even eliminate cancer...

Now, the next two steps have also obtained clear experimental results. Why did Xu Qiu say that he failed?

Xu Qiu picked out a few pieces of information and said: "You have done cross-analysis of the crown group, transcriptome, proteome, phosphorylation modification group and multiple spatial omics...

"The result is of course good, which clarifies the drugability and novelty of cdk20.

"But it is precisely because you are too focused on the relationship between cdk20 and hepatocellular carcinoma that you have overlooked one thing - many data in the experiments show that cdk20 shows a tendency to overexpress in many human tissues and tumor tissues!"

Everyone present was stunned.

Han Chang shivered. He quickly grabbed a few pieces of information in Xu Qiu's hand to check it. The more he read it, the ugly the expression became. Finally, he sighed and handed the information to the next person silently.

Soon, the whole laboratory fell silent.

They have conducted countless analysis and research on the CDK20 molecule to confirm that this target can be atomized by small molecules. Moreover, no phase one clinical trials have been conducted in the context of any disease in the past three years, nor have they been targeted for previously approved drugs.

This means that the CDK20 molecule is extremely novel and if it succeeds, it is definitely an original medicine.

The subsequent research, because Xu Qiu had screened it, and the pressure of completing the work for five months was hanging over their heads, they were trying to find the connection between the CDK20 molecule and hepatocellular carcinoma...

From here, they went into serious fallacy - at the beginning of scientific research, they actually assumed the conclusion that cdk20 is related to hepatocellular carcinoma, and how can it not make any mistakes when using the conclusion to reverse the process!

Xu Qiu gave a further explanation, saying: "From your previous research, a lot of evidence can show that the CDK20 molecule may be overexpressed in a large number of tumor cell lines. For example, colorectal cancer, lung cancer, ovarian cancer, etc., hepatocellular carcinoma is just one of them..."

The key to targeting drugs is the word "target". If there are targets everywhere, it is equivalent to no target.

"Cdk20 is a misunderstanding!" Han Chang broke out in cold sweat.

If Xu Qiu had not reminded them to do their own research, they might have spent several years on this molecule and found nothing until the end!

This is the vision and ability of the person in charge of scientific research projects that often determine success or failure... With Xu Qiu's inspection, they can lead countless steps in the early stage!

"Doctor Xu, I'm sorry..." Han Chang and others stood there. They could have avoided this mistake, but they were too eager to achieve it.

"Scientific research is to find a not-so-bad path from the wrong path, and finally gradually approach the truth. Continue to the test of the next target."

Xu Qiu waved his hand, turned around and went to other floors to guide the work of the remaining six teams.

...

The next day, Baiyun Pharmaceutical Factory held a shareholders' meeting, and at the meeting, it sold the excess venues and equipment unanimously to support Xu Qiu's research and development work.

However, this proposal was rejected as soon as it was delivered to Xu Qiu's table.

Five billion, five months should be enough.

"In the past half a month, we only spent 300 million yuan, but now it is the most expensive stage to determine the target. In the future, we will match pilot compounds and find drug ratios. The daily funding may exceed 100 million yuan!" Linyi Finance Director analyzed.

"It's okay."

Xu Qiu was not worried about this... The cost of matching the ratio of pilot compounds and drugs lies in constant trial and error. Among the 100,000 combinations, one hundred solutions with certain efficacy may be found, and only three or four of them are truly valuable.

But after mastering the divine scientific research capabilities, Xu Qiu had the ability to reduce the "100,000" to "1,000" or even "500".

There are 100 five hundred available, and three or four have clinical significance. This is a capability that all pharmaceutical companies envy!

The savings are even more astronomical, which can be controlled from hundreds of millions of dollars a day to tens of millions of dollars.

The R&D speed is unimaginable...

...

A few days later, Fang Wenwen, who had just undergone a liver transplant, had her physical signs stabilized.

But on the other hand, after 60% of the liver was removed, Qiu Qinghu's condition was getting worse day by day.

His surgery was very successful, but sigmoid cancer was eroding the only vitality he had left at every moment, just like a candle in the wind that would be extinguished at any time.

"Doctor Xu, I want to go to ICU to see her." During a round on the fourth day of the operation, Qiu Qinghu suddenly struggled to get up and said while gasping.

His skin was twitching slightly, and the severe cancer pain had penetrated into his bones, causing him to almost no sleep, but Qiu Qinghu still squeezed out a smile.

"Okay." Xu Qiu nodded.

Half an hour later, at Xu Qiu's instruction, Qiu Qinghu came to the intensive care unit wearing an isolation suit and saw Fang Wenwen lying on the bed.

The two held each other's hand through sterile gloves and wanted to hug them, but the various tubes on Fang Wenwen and the isolation suits worn by Qiu Qinghu were unable to make them do what they wanted.

"Get good." Qiu Qinghu grinned and ordered.

Fang Wenwen lowered her head slightly and said, "Okay, I will definitely get better. We will go to the beach to play in the future. We live in Linhai City. We have never been to the beach before..."

Qiu Qinghu smiled and waved his hand to end the brief visit.

The next morning, when the nurse was routinely handing over the pre-shift care routinely, she was frightened to find Qiu Qinghu’s bed empty!

I searched the entire ward, but there was no trace.

She quickly sent a message to the nursing department and called the ICU.

Soon, nurse icu hurried to Fang Wenwen's ward to check it out, but found nothing, and came outside the icu again.

As a result, I saw a figure sitting in the distance at a glance.

He leaned against the corner of the wall in the ICU corridor, very tall, but his body was morbid and thin.

People around the neighborhood came and went, but didn't pay much attention.

The cruelest world outside the icu is, sleeping on the ground, sitting on a chair all night, or laying a few newspapers as beds. It is not surprising that in order to save the family members of the icu for money, the people here have tried their best.

But nurse ICU recognized Qiu Qinghu with his cuffs in the corner at a glance, curled up into a ball of Qiu Qinghu who fell in the corner.
Chapter completed!
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